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The local intracerebral infusion (i.c.) of 2 mg/kg per day of furegrelate is more effective than 0.5 mg/kg per day on established human U87 glioblastoma xenografts in nude mice. (A) The local delivery of 2 mg/kg per day of furegrelate reduced the tumor growth of U87 human glioblastoma xenografts by 73.1% (*P
Kaplan-Meier survival curve of human U87 glioblastoma-bearing nude mice. The local intracerebral microinfusion (i.c.) of furegrelate at 2 mg/kg per day from day 8 to 36 in combination with a BCNU chemotherapy administered i.p. at 15 mg/kg per day from day 10 to 14 further increased the survival benefits of BCNU therapy (P
Jakubowska, Monika, Michalczyk-Wetula, Dominika, Pyka, Janusz, Susz, Anna, Urbanska, Krystyna, Plonka, Beata K., Kuleta, Patryk, Lacki, Piotr, Krzykawska-Serda, Martyna, Fiedor, Leszek and Plonka, Przemyslaw M. 2013. Nitrosylhemoglobin in photodynamically stressed human tumors growing in nude mice. Nitric Oxide 35 , pp. 79-88. 10.1016/j.niox.2013.08.004
Jakubowska, Monika, Sniegocka, M., Podgorska, E., Michalczyk-Wetula, D., Urbanska, K., Susz, A., Fiedor, L., Pyka, J. and Plonka, P. M. 2013. Pulmonary metastases of the A549-derived lung adenocarcinoma tumors growing in nude mice. A multiple case study. Acta Biochimica Polonica 60 (3) , pp. 323-330.
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